abstract：:Previous studies assessing effect of ischemia on ventricular repolarization are mostly directed toward patients with coronary artery disease (CAD); however, similar reports on cardiac syndrome X (CSX) are scarce. Whether microvascular dysfunction of CSX and ischemia induced by CAD produce comparable effect on ventricu...

journal_title：Frontiers in physiology

authors： Lutfi MF

更新日期：2016-09-21 00:00:00

abstract：:Secondary shifts develop in post-translational phosphorylation of sarcomeric proteins in multiple animal models of inherited cardiomyopathy. These signaling alterations together with the primary mutation are predicted to contribute to the overall cardiac phenotype. As a result, identification and integration of post-t...

journal_title：Frontiers in physiology

authors： Westfall MV

更新日期：2016-09-14 00:00:00

abstract：:Botrytis-induced kinase1 (BIK1), a receptor-like cytoplasmic kinase, plays an important role in resistance against pathogens and insects in Arabidopsis thaliana. However, it remains unknown whether BIK1 functions against Plasmodiophora brassicae, an obligate biotrophic protist that attacks cruciferous plants and induc...

journal_title：Frontiers in physiology

authors： Chen T,Bi K,He Z,Gao Z,Zhao Y,Fu Y,Cheng J,Xie J,Jiang D

更新日期：2016-09-13 00:00:00

abstract：:Melanization reflects not only body color variation but also environmental plasticity. It is a strategy that helps insects adapt to environmental change. Different color morphs may have distinct life history traits, e.g., development time, growth rate, and body weight. The green slender planthopper Saccharosydne proce...

journal_title：Frontiers in physiology

authors： Yin H,Shi Q,Shakeel M,Kuang J,Li J

更新日期：2016-09-12 00:00:00

abstract：:Most sense organs of arthropods are ensconced in small exoskeletal compartments that hinder direct access to plasma membranes. We have developed a method for exposing live sensory and supporting cells in such structures. The technique uses a viscous light cured resin to embed and support the structure, which is then s...

journal_title：Frontiers in physiology

authors： Kay AR,Raccuglia D,Scholte J,Sivan-Loukianova E,Barwacz CA,Armstrong SR,Guymon CA,Nitabach MN,Eberl DF

更新日期：2016-09-12 00:00:00

abstract：:During formation of the secondary palate in mammalian embryos, two vertically oriented palatal shelves rapidly elevate into a horizontal position above the tongue, meet at the midline, and fuse to form a single entity. Previous observations suggested that elevation occurs by a simple 90° rotation of the palatal shelve...

journal_title：Frontiers in physiology

authors： Chiquet M,Blumer S,Angelini M,Mitsiadis TA,Katsaros C

更新日期：2016-09-07 00:00:00

abstract：:Myocardial electrical impedance is a biophysical property of the heart that is influenced by the intrinsic structural characteristics of the tissue. Therefore, the structural derangements elicited in a chronic myocardial infarction should cause specific changes in the local systolic-diastolic myocardial impedance, but...

journal_title：Frontiers in physiology

authors： Amorós-Figueras G,Jorge E,García-Sánchez T,Bragós R,Rosell-Ferrer J,Cinca J

更新日期：2016-08-31 00:00:00

abstract：:Malignant hypertension develops in some cases of hypertension but not in others. We hypothesized that an impaired neovascularization and a reduced capillary supply characterizes the malignant course of experimental hypertension. Two-kidney, one-clip renovascular hypertension was induced in rats; controls (sham) were s...

journal_title：Frontiers in physiology

authors： Hartner A,Jagusch L,Cordasic N,Amann K,Veelken R,Jacobi J,Hilgers KF

更新日期：2016-08-30 00:00:00

abstract：:The paper reports application of a Markov-like stochastic process agent-based model and a "virtual farm" concept for enhancement of site-specific Integrated Pest Management. Conceptually, the model represents a "bottom-up ethological" approach and emulates behavior of the "primary IPM actors"-large cohorts of individu...

journal_title：Frontiers in physiology

authors： Lux SA,Wnuk A,Vogt H,Belien T,Spornberger A,Studnicki M

更新日期：2016-08-23 00:00:00

abstract：:Lineage fate decisions of hematopoietic cells depend on intrinsic factors and extrinsic signals provided by the bone marrow microenvironment, where they reside. Abnormalities in composition and function of hematopoietic niches have been proposed as key contributors of acute lymphoblastic leukemia (ALL) progression. Ou...

journal_title：Frontiers in physiology

authors： Enciso J,Mayani H,Mendoza L,Pelayo R

更新日期：2016-08-19 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:Leucine-rich repeat containing protein 10 (LRRC10) is a cardiomyocyte-specific member of the Leucine-rich repeat containing (LRRC) protein superfamily with critical roles in cardiac function and disease pathogenesis. Recent studies have identified LRRC10 mutations in human idiopathic dilated cardiomyopathy (DCM) and L...

journal_title：Frontiers in physiology

authors： Brody MJ,Lee Y

更新日期：2016-08-03 00:00:00

abstract：:The pea aphid, Acyrthosiphon pisum (Harris) (Hemiptera: Aphididae), shows wing polyphenism (winged and wingless morphs) in its life cycle. The winged morph is adapted for dispersal; its two developmental adult stages (for dispersal and reproduction) are based on its breeding periods. The two morphs show different phot...

journal_title：Frontiers in physiology

authors： Zhang Y,Wang XX,Jing X,Tian HG,Liu TX

更新日期：2016-08-02 00:00:00

abstract：PURPOSE:While the intention of endurance athletes undertaking short term heat training protocols is to rapidly gain meaningful physical adaption prior to competition in the heat, it is currently unclear whether or not this process also presents an overt, acute challenge to the immune system. The aim of this study was t...

journal_title：Frontiers in physiology

authors： Guy JH,Pyne DB,Deakin GB,Miller CM,Edwards AM

更新日期：2016-07-29 00:00:00

abstract：:Defects in mid-facial development, including cleft lip/palate, account for a large number of human birth defects annually. In many cases, aberrant gene expression results in either a reduction in the number of neural crest cells (NCCs) that reach the frontonasal region and form much of the facial skeleton or subsequen...

journal_title：Frontiers in physiology

authors： Ding HL,Hooper JE,Batzel P,Eames BF,Postlethwait JH,Artinger KB,Clouthier DE

更新日期：2016-07-14 00:00:00

abstract：:Extracellular ATP acts on the P2X family of ligand-gated ion channels and several members of the P2Y family of G protein-coupled receptors to mediate intercellular communication among many cell types including bone-forming osteoblasts. It is known that multiple P2 receptors are expressed on osteoblasts (P2X2,5,6,7 and...

journal_title：Frontiers in physiology

authors： Xing S,Grol MW,Grutter PH,Dixon SJ,Komarova SV

更新日期：2016-07-13 00:00:00

abstract：:Zymogens are delivered to the arterial wall by radial transmural convection. Plasminogen can be activated within the arterial wall to produce plasmin, which is involved in evolution of the atherosclerotic plaque. Vascular smooth muscle cells (vSMCs) protect the vessels from proteolytic injury due to atherosclerosis de...

journal_title：Frontiers in physiology

authors： Boukais K,Bayles R,Borges Lde F,Louedec L,Boulaftali Y,Ho-Tin-Noé B,Arocas V,Bouton MC,Michel JB

更新日期：2016-06-30 00:00:00

abstract：:The aim of this study was to investigate the effects of two consecutive Crossfit® training sessions (24 h apart) designed to enhance work-capacity that involved both cardiovascular and muscular exercises on cytokines, muscle power, blood lactate and glucose. Nine male members of the CrossFit® community (age 26.7 ± 6.6...

journal_title：Frontiers in physiology

authors： Tibana RA,de Almeida LM,Frade de Sousa NM,Nascimento Dda C,Neto IV,de Almeida JA,de Souza VC,Lopes Mde F,Nobrega Ode T,Vieira DC,Navalta JW,Prestes J

更新日期：2016-06-28 00:00:00

abstract：:Large-conductance calcium-activated potassium (BK) channels are currently considered as vital players in a variety of renal physiological processes. In podocytes, BK channels become active in response to stimuli that increase local cytosolic Ca(2+), possibly secondary to activation of slit diaphragm TRPC6 channels by ...

journal_title：Frontiers in physiology

authors： Tao J,Lan Z,Wang Y,Hei H,Tian L,Pan W,Zhang X,Peng W

更新日期：2016-06-21 00:00:00

abstract：:Different from other epithelia, the intestinal epithelium has the complex task of providing a barrier impeding the entry of toxins, food antigens, and microbes, while at the same time allowing for the transfer of nutrients, electrolytes, water, and microbial metabolites. These molecules/organisms are transported eithe...

journal_title：Frontiers in physiology

authors： Tang L,Cheng CY,Sun X,Pedicone AJ,Mohamadzadeh M,Cheng SX

更新日期：2016-06-21 00:00:00

abstract：PURPOSE:Breathlessness is a complex set of symptoms that are comprised of both sensory and affective (emotional) dimensions. While ventilation is now understood to be a potential limiter to performance in highly-trained individuals, the contribution of breathlessness-anxiety in those nearing maximal ventilation during ...

journal_title：Frontiers in physiology

authors： Faull OK,Cox PJ,Pattinson KT

更新日期：2016-06-16 00:00:00

abstract：AIMS:It has been previously shown that the probiotic kefir (a symbiotic matrix containing acid bacteria and yeasts) attenuated the hypertension and the endothelial dysfunction in spontaneously hypertensive rats (SHR). In the present study, the effect of chronic administration of kefir on the cardiac autonomic control o...

journal_title：Frontiers in physiology

authors： Klippel BF,Duemke LB,Leal MA,Friques AG,Dantas EM,Dalvi RF,Gava AL,Pereira TM,Andrade TU,Meyrelles SS,Campagnaro BP,Vasquez EC

更新日期：2016-06-07 00:00:00

abstract：:Odorant binding proteins (OBPs) are proposed to be directly required for odorant discrimination and represent potential interesting targets for pest control. In the notoriously agricultural pest Adelphocoris lineolatus, our previous functional investigation of highly expressed antennal OBPs clearly supported this view...

journal_title：Frontiers in physiology

authors： Sun L,Wei Y,Zhang DD,Ma XY,Xiao Y,Zhang YN,Yang XM,Xiao Q,Guo YY,Zhang YJ

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Exercise reduces arterial and central venous blood pressures during recovery, which contributes to its valuable anti-hypertensive effects and to facilitating hypervolemia. Repeated sprint exercise potently improves metabolic function, but its cardiovascular effects (esp. hematological) are less well-charac...

journal_title：Frontiers in physiology

authors： Graham MJ,Lucas SJ,Francois ME,Stavrianeas S,Parr EB,Thomas KN,Cotter JD

更新日期：2016-05-31 00:00:00

abstract：:Sarcomere lengths have been a crucial outcome measure for understanding and explaining basic muscle properties and muscle function. Sarcomere lengths for a given muscle are typically measured at a single spot, often in the mid-belly of the muscle, and at a given muscle length. It is then assumed implicitly that the sa...

journal_title：Frontiers in physiology

authors： Moo EK,Fortuna R,Sibole SC,Abusara Z,Herzog W

更新日期：2016-05-25 00:00:00

abstract：:Gene-targeted deletion of the potassium channel Kv1.3 (Kv1.3(-∕-)) results in "Super-smeller" mice with a sensory phenotype that includes an increased olfactory ability linked to changes in olfactory circuitry, increased abundance of olfactory cilia, and increased expression of odorant receptors and the G-protein, Gol...

journal_title：Frontiers in physiology

authors： Kovach CP,Al Koborssy D,Huang Z,Chelette BM,Fadool JM,Fadool DA

更新日期：2016-05-19 00:00:00

abstract：:Obstructive sleep apnea (OSA), manifested by exposure to chronic intermittent hypoxia (CIH) and excess production of reactive oxygen species (ROS) in the airways, is associated with hyperreactive airway diseases. ROS, particularly when created by NADPH oxidase, are known to sensitize lung vagal C fibers (LVCFs), which...

journal_title：Frontiers in physiology

authors： Yang CH,Zhuang WL,Shen YJ,Lai CJ,Kou YR

更新日期：2016-05-09 00:00:00

abstract：:Co-expressed genes often share similar functions, and gene co-expression networks have been widely used in studying the functionality of gene modules. Previous analysis indicated that genes are more likely to be co-expressed if they are either regulated by the same transcription factors, forming protein complexes or s...

journal_title：Frontiers in physiology

authors： Zhang C,Lee S,Mardinoglu A,Hua Q

更新日期：2016-05-02 00:00:00

abstract：:Although cardiac recovery is an important criterion for ranking horses in endurance competitions, heart rate variability (HRV) has hardly ever been studied in the context of this equestrian discipline. In the present study, we sought to determine whether HRV is affected by parameters such as age, exercise duration and...

journal_title：Frontiers in physiology

authors： Younes M,Robert C,Barrey E,Cottin F

更新日期：2016-05-02 00:00:00

abstract：:In aged subjects, late-onset Alzheimer's disease (LOAD) starts in the lateral entorhinal allocortex where a failure of clearance mechanisms triggers an accumulation of neurotoxic amyloid-β42 oligomers (Aβ42-os). In neurons and astrocytes, Aβ42-os enhance the transcription of Aβ precursor protein (APP) and β-secretase/...

journal_title：Frontiers in physiology

authors： Chiarini A,Armato U,Liu D,Dal Prà I

更新日期：2016-04-26 00:00:00

abstract：:Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH levels on the energy metabolism is unclear. The aim of the present study was to inves...

journal_title：Frontiers in physiology

authors： Lavoie S,Steullet P,Kulak A,Preitner F,Do KQ,Magistretti PJ

更新日期：2016-04-21 00:00:00

abstract：:We present a first description of the distribution and characterization of epitheliocystis infections in brown trout (Salmo trutta) from the upper catchments of two major European rivers, the Rhine and the Rhone. Overall, epitheliocystis was widely distributed, with 70% of the Rhine and 67% of the Rhone sites harborin...

journal_title：Frontiers in physiology

authors： Guevara Soto M,Vaughan L,Segner H,Wahli T,Vidondo B,Schmidt-Posthaus H

更新日期：2016-04-18 00:00:00

abstract：:Blood pressure regulation is a prime example of homeostatic regulation. However, some characteristics of the cardiovascular system better match a non-linear self-organized system than a homeostatic one. To determine whether blood pressure regulation is self-organized, we repeated the seminal demonstration of self-orga...

journal_title：Frontiers in physiology

authors： Fortrat JO,Levrard T,Courcinous S,Victor J

更新日期：2016-03-31 00:00:00

abstract：PURPOSE:We investigated if oral ingestion of ibuprofen influenced leucocyte recruitment and infiltration following an acute bout of traditional resistance exercise Methods: Sixteen male subjects were divided into two groups that received the maximum over-the-counter dose of ibuprofen (1200mg d(-1)) or a similarly admin...

journal_title：Frontiers in physiology

authors： Vella L,Markworth JF,Paulsen G,Raastad T,Peake JM,Snow RJ,Cameron-Smith D,Russell AP

更新日期：2016-03-29 00:00:00

abstract：:Rapamycin, also known as sirolimus, is an antifungal agent and immunosuppressant drug used to prevent organ rejection in transplantation. However, little is known about the role of rapamycin in cardiac hypertrophy and the signaling pathways involved. Here, the effect of rapamycin was examined using phenylephrine (PE) ...

journal_title：Frontiers in physiology

authors： Gu J,Hu W,Song ZP,Chen YG,Zhang DD,Wang CQ

更新日期：2016-03-18 00:00:00

abstract：AIM:The aim of the present study was to analyze the response of vascular circulating microRNAs (miRNAs; miR-16, miR-21, miR-126) and the VEGF mRNA following an acute bout of HIIT and HVT in children. METHODS:Twelve healthy competitive young male cyclists (14.4 ± 0.8 years; 57.9 ± 9.4 ml·min(-1)·kg(-1) peak oxygen upta...

journal_title：Frontiers in physiology

authors： Kilian Y,Wehmeier UF,Wahl P,Mester J,Hilberg T,Sperlich B

更新日期：2016-03-14 00:00:00

abstract：BACKGROUND:The potential for cross acclimation between environmental stressors is not well understood. Thus, the aim of this investigation was to determine the effect of fixed-workload heat or hypoxic acclimation on cellular, physiological, and performance responses during post acclimation hypoxic exercise in humans. ...

journal_title：Frontiers in physiology

authors： Lee BJ,Miller A,James RS,Thake CD

更新日期：2016-03-08 00:00:00

abstract：:We investigate analytically the production of entropy during a breathing cycle in healthy and diseased lungs. First, we calculate entropy production in healthy lungs by applying the laws of thermodynamics to the well-known transpulmonary pressure-volume (P-V) curves of the lung under the assumption that lung tissue be...

journal_title：Frontiers in physiology

authors： Oliveira CL,Araújo AD,Bates JH,Andrade JS Jr,Suki B

更新日期：2016-03-01 00:00:00

abstract：:Tyrophagus putrescentiae (Schrank, 1781) is an emerging source of allergens in stored products and homes. Feces proteases are the major allergens of astigmatid mites (Acari: Acaridida). In addition, the mites are carriers of microorganisms and microbial adjuvant compounds that stimulate innate signaling pathways. We s...

journal_title：Frontiers in physiology

authors： Erban T,Rybanska D,Harant K,Hortova B,Hubert J

更新日期：2016-02-24 00:00:00

abstract：:Regular physical exercise provides many health benefits, protecting against the development of chronic diseases, and improving quality of life. Some of the mechanisms by which exercise provides these effects are the promotion of an anti-inflammatory state, reinforcement of the neuromuscular function, and activation of...

journal_title：Frontiers in physiology

authors： Cerdá B,Pérez M,Pérez-Santiago JD,Tornero-Aguilera JF,González-Soltero R,Larrosa M

更新日期：2016-02-18 00:00:00